Iowa State vs Arizona Prediction, Odds & Props

College Football · Week 9 · Sat, Oct 24 · 7:30 PM ET

Iowa State Cyclones

Away · 3-3

Arizona Wildcats

Home · 5-1

Current lines

Spread: ARIZ -10
Total: 50.5
Moneyline: ISU +285 / ARIZ -325

Best available price across major books when this page updated.

Scouting report

Sprinkle's read:Arizona -10 spread★★★★

Laying 10 with the better team

Arizona are laying 10, a number they have cleared in four of their last six. Arizona is No.

The number

A win by 10 or less is a loss on this ticket; it needs a comfortable margin, not just the result.

The decider

Arizona's offense meets an Iowa State defense that has been average; the edge in that matchup belongs to Arizona. Arizona score 35.7 a game and Iowa State allow 21.7.

Situational

Iowa State are missing Dominic Overby (WR), Rylan Barnes (TE); Arizona are missing Chris Hunter III (WR), Dwight Bootle II (CB) — worth a notch of caution.

What breaks this

Iowa State have been the cleaner team with the ball, and in a close game that is usually the difference.

Iowa State Cyclones

Last five

L10-24 @ BYU
W45-42 vs WVU
L17-31 vs UTAH
W55-7 vs BGSU
L13-16 @ IOWA

Out

Dominic Overby, WR (Knee)
Willie Breland III, LB (Knee)
Rylan Barnes, TE
Carter Pabst, WR
Micah Harper, S
Evan Boyd, WR

Arizona Wildcats

Last five

W52-31 @ WVU
W34-7 vs CIN
W34-24 @ WSU
W42-17 vs NIU
L17-28 @ BYU

Out

Chris Hunter III, WR (Knee)
Dwight Bootle II, CB (Foot)
Jabari Mann, LB (Knee)
Tre Spivey, WR (Foot)
Cole Rusk, TE (Ankle)
Hannibal Navies II, S (Ankle)

Top-rated props in this game

Arizona

Spread

Iowa State D allowing 22 ppg L6 • 5.7 yds/play allowed
Arizona No. 22, Iowa State No. 34 by our ratings • this spot covers 63% of 84 games
Last met 2025: Iowa State won 39-14

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